SCHEMBL1613644

SCHEMBL1613644

N[C@H](Cc1ccc(F)c(F)c1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.62
PTGS1 P23219 2/20 0.62
KDM4E B2RXH2 1/20 0.62
USP2 O75604 1/20 0.62
EGFR P00533 1/20 0.62
LCK P06239 1/20 0.62
FYN P06241 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
ALOX15 P16050 1/20 0.62
HTR2A P28223 1/20 0.62
PTGS2 P35354 1/20 0.62
RECQL P46063 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
PKM P14618 2/20 0.56
ALPI P09923 1/20 0.56
XIAP P98170 1/20 0.56
GRB2 P62993 1/20 0.53
PTPN1 P18031 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29481457 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL18511382 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL44052 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL29478416 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL44051 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL23013168 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL29481456 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL28025299 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL23013165 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL22557028 0.92 SLC7A5 (0.54) SLC7A5PTGS1KDM4EUSP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368224-A1 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS OHIO STATE INNOVATION FOUNDATION 2024-11-07 US claimed
EP-4358989-A2 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS Ohio State Innovation Foundation (US) 2024-05-01 EP claimed
WO-2022271810-A2 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS OHIO STATE INNOVATION FOUNDATION (US) 2022-12-29 WO claimed
US-20160022636-A1 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2016-01-28 US claimed
EP-2968240-A2 PHYSIOLOGICAL LIGANDS FOR GPR139 Janssen Pharmaceutica, N.V. (BE) 2016-01-20 EP claimed
US-20140336216-A1 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2014-11-13 US claimed
WO-2014152917-A2 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2014-09-25 WO claimed
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY TRANSFERT PLUS LP (CA) 2026-03-26 US disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 US disclosed
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 WO disclosed
US-20250325469-A1 Inhibitors of atp synthase - cosmetic and therapeutic uses FORREST MICHAEL DAVID (GB) 2025-10-23 US disclosed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US disclosed
US-6610730-B2 Viricides; protease inbhibitor AGOURON PHARMACEUTICALS, INC. 2003-08-26 US disclosed
US-6514997-B2 Block the activity of picornaviral 3C protease AGOURON PHARMACEUTICALS, INC. 2003-02-04 US disclosed
EP-1252145-A1 ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2002-10-30 EP disclosed
US-20010047006-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis AGOURON PHARMACEUTICALS, INC. 2001-11-29 US disclosed
WO-2001040189-A1 ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2001-06-07 WO disclosed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP disclosed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 SLC7A5 1405/4885PTGS1 1907/4885KDM4E 848/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B SLC7A5 1050/4885PTGS1 2516/4885KDM4E 2142/4885
US-20240368224-A1 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS KRAS, HRAS, NRAS SLC7A5 2938/4885PTGS1 3299/4885KDM4E 4608/4885
US-20250325469-A1 Inhibitors of atp synthase - cosmetic and therapeutic uses ATP5F1A, ATP5F1B, ATP5ME SLC7A5 470/4885PTGS1 1055/4885KDM4E 4143/4885
US-20010047006-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis RNASE1, SERPINB1, RNASEH1 SLC7A5 3338/4885PTGS1 1739/4885KDM4E 2980/4885
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY VSIG8, MICA, CD74 SLC7A5 1741/4885PTGS1 3808/4885KDM4E 2895/4885
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R SLC7A5 2654/4885PTGS1 1751/4885KDM4E 2986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.