Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458815 | 0.95 | CYP1A1 (0.54) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL3693998 | 0.95 | CYP1A1 (0.54) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL439445 | 0.95 | CYP1A1 (0.58) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL29358046 | 0.93 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL184973 | 0.93 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL29373621 | 0.93 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL13458693 | 0.93 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL13458682 | 0.90 | CYP1A1 (0.49) | CYP1A1CYP1B1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL17899330 | 0.90 | ACACA (0.50) | ACACAAURKAAURKBALDH1A1HPGD | |
| SCHEMBL3698074 | 0.90 | ACACA (0.50) | ACACAAURKAAURKBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436341-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-07 | — | — | US | disclosed |
| US-8436341-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-07 | — | — | US | disclosed |
| US-8309731-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-8309731-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120065402-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065402-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20100207108-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100207108-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010075379-A2 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065402-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | PAH, AHR, TYR | CYP1A1 15/4885CYP1B1 97/4885CYP11B1 1583/4885 |
| US-20100207108-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | PAH, AHR, TYR | CYP1A1 14/4885CYP1B1 93/4885CYP11B1 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.