Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 5/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661623 | 0.87 | PER2 (0.42) | PER2TBXA2RCNR2TP53CRY2 | |
| SCHEMBL1666151 | 0.81 | PER2 (0.43) | PER2TBXA2RTP53CRY2 | |
| SCHEMBL661075 | 0.80 | PER2 (0.42) | PER2TBXA2RCNR2CRY2 | |
| SCHEMBL662280 | 0.79 | PER2 (0.44) | PER2CNR2CRY2 | |
| SCHEMBL661691 | 0.78 | PER2 (0.43) | PER2CNR2CRY2 | |
| SCHEMBL664100 | 0.78 | CCR3 (0.43) | PER2TBXA2RCNR2CRY2 | |
| SCHEMBL662275 | 0.75 | CNR2 (0.38) | PER2CNR2TP53MAPTKDM4E | |
| SCHEMBL4405451 | 0.74 | PER2 (0.37) | PER2TBXA2RTP53CRY2MAPT | |
| SCHEMBL663094 | 0.74 | PER2 (0.41) | PER2TBXA2RCNR2CRY2 | |
| SCHEMBL661470 | 0.73 | RORC (0.39) | CNR2TP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |