Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902153 | 0.88 | HTR2A (0.35) | PIM1HTR2AGRIN1GRIN2AGRIN2B | |
| SCHEMBL5668191 | 0.84 | KDM4E (0.40) | HTR1AMEN1KMT2ACYP2D6 | |
| SCHEMBL31202626 | 0.83 | KDM4E (0.42) | HTR1AMEN1KMT2ACYP2D6 | |
| SCHEMBL9158078 | 0.83 | KDM4E (0.42) | HTR1AMEN1KMT2ACYP2D6 | |
| SCHEMBL16836340 | 0.82 | DRD2 (0.37) | HTR2ASIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL29984959 | 0.81 | CHRM2 (0.33) | HTR2ASIGMAR1CHRM2HTR1AADRA2A | |
| Iodide SCHEMBL31598452 | 0.81 | KDM4E (0.41) | HTR1AMEN1KMT2ACYP2D6 | |
| Bromide SCHEMBL28420922 | 0.81 | ALDH1A1 (0.44) | HTR1AMEN1KMT2ACYP2D6 | |
| Iodide SCHEMBL31603902 | 0.81 | KDM4E (0.41) | HTR1AMEN1KMT2ACYP2D6 | |
| Bromide SCHEMBL31186953 | 0.81 | ALDH1A1 (0.44) | HTR1AMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946635-A2 | LOCALLY ACTING TOLL-LIKE RECEPTOR 7 (TLR7) AND/OR TLR8 AGONIST IMMUNOTHERAPY COMPOUNDS AND THEIR USES | ALTIMMUNE UK LIMITED (GB) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020205996-A2 | LOCALLY ACTING TOLL-LIKE RECEPTOR 7 (TLR7) AND/OR TLR8 AGONIST IMMUNOTHERAPY COMPOUNDS AND THEIR USES | ALTIMMUNE UK LTD (GB) | 2020-10-08 | — | — | WO | disclosed |
| US-20090325108-A1 | COLOR PHOTOGRAPHIC MATERIALS WITH MAGENTA MINIMUM DENSITY DYES | LASER PACIFIC MEDIA CORPORATION | 2009-12-31 | — | — | US | disclosed |
| US-7632632-B1 | Color photographic materials with magenta minimum density dyes | EASTMAN KODAK COMPANY (US) | 2009-12-15 | — | — | US | disclosed |