Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 9/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468331 | 0.91 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2469428 | 0.91 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2467306 | 0.89 | ALDH1A1 (0.45) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2471276 | 0.89 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2468321 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2470694 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2472012 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2468186 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2468237 | 0.85 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2AMEN1KCNA3 | |
| SCHEMBL2469459 | 0.85 | SLC6A9 (0.44) | ALDH1A1HPGDKMT2AMEN1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312307-A1 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312307-A1 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | KCNJ2, KCNH2, KCNQ5 | ALDH1A1 3941/4885HPGD 1527/4885KMT2A 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.