Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.86 |
| ▸ | CNR2 | P34972 | 5/20 | 0.86 |
| ▸ | CNR1 | P21554 | 1/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 8/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186377 | 0.81 | CNR2 (0.59) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4404110 | 0.81 | TRPV1 (0.59) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4405605 | 0.80 | HDAC6 (0.68) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4407827 | 0.79 | CNR2 (0.56) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4407046 | 0.77 | TRPV1 (0.55) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4408047 | 0.77 | TRPV1 (0.54) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4411302 | 0.76 | CNR2 (0.54) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4407064 | 0.75 | CNR2 (0.52) | TRPV1CNR2CNR1HDAC6MGLL | |
| SCHEMBL4407341 | 0.75 | TRPV1 (0.59) | TRPV1CNR2CNR1ALDH1A1RAB9A | |
| SCHEMBL4407355 | 0.74 | RAB9A (0.54) | TRPV1CNR2CNR1HDAC6DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |