Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923738 | 0.83 | LMNA (0.68) | TRPV1CNR1CNR2RAB9AMEN1 | |
| SCHEMBL2619292 | 0.79 | SMN1; SMN2 (0.68) | RAB9AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL24948886 | 0.79 | LMNA (0.59) | TRPV1CNR1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4923728 | 0.78 | TRPV1 (0.49) | TRPV1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1450062 | 0.77 | ALDH1A1 (0.51) | TRPV1CNR1CNR2L3MBTL1MEN1 | |
| SCHEMBL4405908 | 0.76 | RAB9A (0.61) | RAB9AL3MBTL1HPGDATMSMN1; SMN2 | |
| SCHEMBL513787 | 0.76 | RAB9A (0.61) | RAB9AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL23625644 | 0.76 | RAB9A (0.65) | RAB9AL3MBTL1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4412228 | 0.75 | RAB9A (0.59) | RAB9AL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL4407129 | 0.75 | TRPV1 (0.86) | TRPV1CNR1CNR2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| CN-101155780-A | Hydroxamates as histone deacetylase inhibitors and pharmaceutical formulations containing them | MENARINI INT OPERATIONS LU SA (LU) | 2008-04-02 | — | — | CN | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |