SCHEMBL4407159

SCHEMBL4407159

CC(C)(C)Cc1nnnn1Cl

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.35
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408150 0.76 ALDH1A1 (0.39) FAAHALDH1A1LMNA
SCHEMBL4400131 0.75 ALDH1A1 (0.38) FAAHALDH1A1LMNANPSR1
SCHEMBL27022866 0.74 ALDH1A1 (0.33) FAAHALDH1A1
SCHEMBL4405008 0.74 LMNA (0.33) FAAHALDH1A1LMNA
SCHEMBL4403787 0.74 ALDH1A1 (0.33) FAAHALDH1A1
SCHEMBL4406689 0.74 ALDH1A1 (0.44) FAAHALDH1A1LMNA
SCHEMBL4407852 0.74 ALDH1A1 (0.51) FAAHALDH1A1LMNANPSR1
SCHEMBL4671811 0.74 ALDH1A1 (0.31) ALDH1A1LMNANPSR1L3MBTL1
SCHEMBL4414869 0.71
SCHEMBL4403800 0.71 ALDH1A1 (0.41) ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed