Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403529 | 0.87 | L3MBTL1 (0.44) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL20798533 | 0.83 | TP53 (0.40) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL470419 | 0.82 | ACHE (0.44) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL17792449 | 0.80 | ACHE (0.43) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL18812610 | 0.79 | L3MBTL1 (0.41) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL7950326 | 0.78 | ACHE (0.41) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL8385833 | 0.78 | TP53 (0.43) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL3872825 | 0.78 | TP53 (0.43) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL14277678 | 0.77 | ACHE (0.45) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL11445579 | 0.77 | ACHE (0.40) | TP53TDP1ACHEL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395010-B1 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA Technologies S à r l (CH) | 2016-07-13 | — | — | EP | disclosed |
| EP-1996598-B1 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE | INVISTA TECH SARL (CH) | 2013-10-16 | — | — | EP | disclosed |
| US-8178711-B2 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A R.L. (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178711-B2 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A R.L. (US) | 2012-05-15 | — | — | US | disclosed |
| EP-1567468-B1 | A SELECTIVE SYNTHESIS OF ORGANOPHOSPHITES | INVISTA TECH SARL (CH) | 2011-03-16 | — | — | EP | disclosed |
| US-20100076212-A1 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE | INVISTA NORTH AMERICA S.A R.L. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100076212-A1 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE | INVISTA NORTH AMERICA S.A R.L. (US) | 2010-03-25 | — | — | US | disclosed |
| US-7629484-B2 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A.R.L. (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629484-B2 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A.R.L. (US) | 2009-12-08 | — | — | US | disclosed |
| US-20070219386-A1 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A R.L. (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070219386-A1 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A R.L. (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219386-A1 | Method for the purification of triorganophosphites by treatment with a basic additive | HRH3, PHOSPHO1, HRH4 | TP53 3729/4885TDP1 2668/4885ACHE 620/4885 |
| US-20100076212-A1 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE | HRH3, PHOSPHO1, HRH4 | TP53 3729/4885TDP1 2668/4885ACHE 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.