Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406817 | 0.95 | HSD11B1 (0.54) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL4413278 | 0.94 | HSD11B1 (0.52) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL22716411 | 0.94 | HSD11B1 (0.52) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL4414691 | 0.90 | HSD11B1 (0.57) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL4675275 | 0.86 | HSD11B1 (0.64) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL14438051 | 0.84 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1NPSR1CYP1A2 | |
| SCHEMBL156901 | 0.82 | HTT (0.60) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL10675268 | 0.81 | HSD11B1 (0.53) | HSD11B1ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10681785 | 0.81 | HSD11B1 (0.47) | HSD11B1HTTPKMNLRP3ALDH1A1 | |
| SCHEMBL96765 | 0.81 | HSD11B1 (0.56) | HSD11B1HTTPKMNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |