Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246137 | 0.84 | ALOX15 (0.41) | — | |
| SCHEMBL5600672 | 0.84 | ALOX15 (0.41) | — | |
| Acrylic Acid SCHEMBL6129261 | 0.78 | ALOX15 (0.36) | TSHRLMNA | |
| SCHEMBL5499975 | 0.76 | — | — | |
| SCHEMBL5255471 | 0.73 | LMNA (0.46) | ADRA1ATSHRLMNASLC22A6PRMT1 | |
| SCHEMBL1489813 | 0.71 | HPGD (0.32) | TSHR | |
| SCHEMBL8071373 | 0.71 | LMNA (0.32) | TSHRLMNASLC22A6AKR1B1NFKB1 | |
| SCHEMBL21791082 | 0.70 | LMNA (0.42) | ADRA1ATSHRLMNASLC22A6PRMT1 | |
| Succinic Acid SCHEMBL17363356 | 0.70 | LMNA (0.42) | LMNAKDM4C | |
| SCHEMBL1537984 | 0.69 | TUBB1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751407-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0751404-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0751405-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| US-5391669-A | Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers | HYDRON LIMITED (GB) | 1995-02-21 | — | — | US | claimed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | claimed |
| EP-1286823-B1 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | COOPERVISION INT HOLDING CO LP (BB) | 2009-06-17 | — | — | EP | disclosed |
| US-7262232-B2 | Ophthalmic lenses and compositions and methods for producing same | COOPERVISION, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-6992118-B2 | Ophthalmic lenses and compositions and methods for producing same | COOPER VISION INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050191335-A1 | Ophthalmic lenses and compositions and methods for producing same | COOPERVISION INC. (US) | 2005-09-01 | — | — | US | disclosed |
| EP-1286823-A4 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | OCULAR SCIENCES INC (US) | 2005-01-12 | — | — | EP | disclosed |
| US-20040046932-A1 | Ophthalmic lenses and compositions and methods for producing same | OCULAR SCIENCES, INC. | 2004-03-11 | — | — | US | disclosed |
| US-6617373-B2 | First crosslinked polymer material which is water swellable, and a second polymeric material physically imobilized by the first | OCULAR SCIENCES, INC. | 2003-09-09 | — | — | US | disclosed |
| US-20020091175-A1 | Ophthalmic lenses and compositions and methods for producing same | OCULAR SCIENCES, INC. | 2002-07-11 | — | — | US | disclosed |
| WO-2001078971-A1 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | OCULAR SCIENCES, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| EP-0751406-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | disclosed |
| EP-0751407-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | disclosed |
| EP-0751405-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | disclosed |
| EP-0751404-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | disclosed |
| US-5391669-A | Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers | HYDRON LIMITED (GB) | 1995-02-21 | — | — | US | disclosed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | disclosed |