SCHEMBL4407659

SCHEMBL4407659

C=CC(=O)Oc1ccc(C(=Cc2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)cc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
MAPT P10636 4/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
TP53 P04637 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 1/20 0.38
PTGS2 P35354 4/20 0.37
THRB P10828 1/20 0.37
HSP90AA1 P07900 1/20 0.37
PDE6D O43924 1/20 0.36
ESR1 P03372 1/20 0.36
RAB9A P51151 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10102821 1.00 CYP2D6 (0.40) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL13777795 1.00 CYP2D6 (0.40) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL13777794 1.00 CYP2D6 (0.40) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL9915758 1.00 CYP2D6 (0.40) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL172200 0.99 KDM4E (0.39) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL2609801 0.94 CYP2D6 (0.42) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL13777756 0.94 CYP2D6 (0.42) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL9915754 0.94 CYP2D6 (0.42) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL9915809 0.94 PTGS2 (0.41) CYP2D6MAPTKDM4EALDH1A1HPGD
SCHEMBL11987115 0.93 PTGS2 (0.44) CYP2D6MAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed