SCHEMBL9915754

SCHEMBL9915754

C=CC(=O)Oc1ccc(/C(=C\c2ccc(N(c3ccccc3)c3ccccc3)cc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.42
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
PTGS2 P35354 4/20 0.40
THRB P10828 2/20 0.40
KMT2A Q03164 3/20 0.39
ESR1 P03372 1/20 0.39
MEN1 O00255 1/20 0.39
HSP90AA1 P07900 1/20 0.39
RAB9A P51151 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B2 P19099 1/20 0.38
NPC1 O15118 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609801 1.00 CYP2D6 (0.42) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL13777756 1.00 CYP2D6 (0.42) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL11987116 0.99 ALDH1A1 (0.42) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL9915682 0.99 THRB (0.40) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL9915809 0.97 PTGS2 (0.41) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL13818605 0.95 KMT2A (0.40) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL10102845 0.95 KMT2A (0.40) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL10102821 0.94 CYP2D6 (0.40) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL13777794 0.94 CYP2D6 (0.40) CYP2D6MAPTALDH1A1KDM4EHPGD
SCHEMBL4407659 0.94 CYP2D6 (0.40) CYP2D6MAPTALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190285997-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8097394-B2 Forming photosensitive layer on electroconductive substrate by spray coating using spray droplets having average diameter (D50) not greater than 10 mu m; abrasion resistance, stable electrical properties, durability RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-8097394-B2 Forming photosensitive layer on electroconductive substrate by spray coating using spray droplets having average diameter (D50) not greater than 10 mu m; abrasion resistance, stable electrical properties, durability RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080124638-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed