Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813803 | 0.80 | HSD17B10 (0.76) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8185281 | 0.79 | HSD17B10 (0.68) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4407874 | 0.78 | HSD17B10 (0.62) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7231445 | 0.78 | HSD17B10 (0.67) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13156344 | 0.77 | HSD17B10 (0.70) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3436150 | 0.77 | HSD17B10 (1.00) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3817327 | 0.76 | HSD17B10 (0.56) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2707387 | 0.75 | LDHA (0.60) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL464409 | 0.75 | HSD17B10 (0.72) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31359187 | 0.75 | HSD17B10 (0.72) | HSD17B10NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135526-A1 | ALPHA-MERCAPTO-AMIDES | NOVARTIS AG (CH) | 2009-11-12 | — | — | WO | disclosed |