Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273758 | 0.88 | SMN1; SMN2 (0.54) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL6268462 | 0.86 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13156344 | 0.83 | HSD17B10 (0.70) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL25143234 | 0.83 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8185281 | 0.82 | HSD17B10 (0.68) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3813803 | 0.81 | HSD17B10 (0.76) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL464409 | 0.78 | HSD17B10 (0.72) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL31359187 | 0.78 | HSD17B10 (0.72) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4407865 | 0.78 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL12569423 | 0.78 | SMN1; SMN2 (0.62) | HSD17B10SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135526-A1 | ALPHA-MERCAPTO-AMIDES | NOVARTIS AG (CH) | 2009-11-12 | — | — | WO | disclosed |