Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | MC5R | P33032 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55837 | 0.98 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL10665140 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL2148044 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Iodide SCHEMBL27877860 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Water SCHEMBL28902586 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL30074811 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Iodide SCHEMBL4618865 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Bromide SCHEMBL887893 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7776250 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Iodide SCHEMBL27877861 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632304-B | A kind of two-photon RNA fluorescence probe and its application in living cells imaging | 山东省科学院新材料研究所 | 2019-03-26 | — | — | CN | disclosed |
| CN-106632304-A | Two-photon RNA (Ribonucleic Acid) fluorescent probe and application thereof in living cell imaging | 山东省科学院新材料研究所 | 2017-05-10 | — | — | CN | disclosed |
| US-20090312325-A1 | Quinoline Derivatives As Phosphodiesterase Inhibitors | BALDWIN IAN ROBERT | 2009-12-17 | — | — | US | disclosed |
| US-20070142373-A1 | Quinoline derivatives as phosphodiesterase inhibitors | GLAXO GROUP LIMITED (GB) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312325-A1 | Quinoline Derivatives As Phosphodiesterase Inhibitors | PDE3B, PDE4B, PDE4A | SMN1; SMN2 3054/4885NPC1 4158/4885RAB9A 211/4885 |
| US-20070142373-A1 | Quinoline derivatives as phosphodiesterase inhibitors | PDE3B, PDE4B, PDE4A | SMN1; SMN2 3054/4885NPC1 4158/4885RAB9A 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.