Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | MC5R | P33032 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27877860 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Iodide SCHEMBL27877861 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL55837 | 0.98 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Iodide SCHEMBL10484701 | 0.96 | TDP1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Water SCHEMBL28902586 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7776250 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL10665140 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL4408280 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| Bromide SCHEMBL887893 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL2148044 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026087600-A1 | STYRYL BENZOTHIAZOLIUM SALTS AND ITS USES AGAINST PARASITIC INFECTIONS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2026-04-30 | — | — | WO | disclosed |
| US-20250130142-A1 | FLUOROGENIC CYANINE COMPOUNDS FOR DETECTING NUCLEIC ACIDS | AAT BIOQUEST, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20250052650-A1 | FLUOROGENIC CYANINE COMPOUNDS FOR DETECTING NUCLEIC ACIDS | AAT BIOQUEST INC (US) | 2025-02-13 | — | — | US | disclosed |
| US-12169166-B2 | Fluorogenic cyanine compounds for detecting nucleic acids | AAT BIOQUEST, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| EP-4261209-A1 | NUCLEIC ACID DETECTION METHOD, COMPOUND AND FLUORESCENT PROBE | Wakayama University (JP) | 2023-10-18 | — | — | EP | disclosed |
| US-20220260464-A1 | FLUOROGENIC CYANINE COMPOUNDS FOR DETECTING NUCLEIC ACIDS | AAT BIOQUEST, INC. | 2022-08-18 | — | — | US | disclosed |
| EP-1893741-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | Beckman Coulter, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1481234-A4 | METHOD AND APPARATUS FOR INCREASING THE DYNAMIC RANGE AND ACCURACY OF BINDING ASSAYS | BECKMAN COULTER INC (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1468107-A4 | METHODS AND REAGENTS FOR IMPROVED CELL-BASED ASSAYS | BECKMAN COULTER INC (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2007001817-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | BECKMAN COULTER, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| WO-2003067212-A2 | METHODS AND REAGENTS FOR CONDUCTING MULTIPLEXED ASSAYS OF MULTIPLE ANALYTES | BECKMAN COULTER, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003036256-A2 | METHOD AND APPARATUS FOR INCREASING THE DYNAMIC RANGE AND ACCURACY OF BINDING ASSAYS | BECKMAN-COULTER, INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| US-20030077569-A1 | Methods and reagents for improved cell-based assays | BECKMAN COULTER, INC. | 2003-04-24 | — | — | US | disclosed |
| US-20030078737-A1 | Method and apparatus for increasing the dynamic range and accuracy of binding assays | BECKMAN COULTER, INC. | 2003-04-24 | — | — | US | disclosed |
| WO-2003034025-A2 | METHODS AND REAGENTS FOR IMPROVED CELL-BASED ASSAYS | BECKMAN-COULTER, INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| US-6495692-B1 | A METHOD FOR SYNTHESIZING DYES EXCITABLE BY A HELIUM-NEON LASER (EXCITABLE AT 633 NM) FROM HOLOLEPIDINES, E. G., 7-HALOLEPIDINE, WHICH DYES ARE SUITABLE FOR THE DETECTION AND ENUMERATION OF RETICULOCYTES IN HUMAN BLOOD SAMPLES. | ABBOTT LABORATORIES | 2002-12-17 | — | — | US | disclosed |
| US-5013638-A | Photographic silver halide element containing small amounts of bromide ions | EASTMAN KODAK COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0365220-A2 | Photographic silver halide material | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-04-25 | — | — | EP | disclosed |
| US-4151162-A | Diazomerocyanines and mesomeric forms thereof | L'OREAL (FR) | 1979-04-24 | — | — | US | disclosed |
| US-3985499-A | Diazamerocyanines for dyeing keratinous fibers | L'OREAL (FR) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250130142-A1 | FLUOROGENIC CYANINE COMPOUNDS FOR DETECTING NUCLEIC ACIDS | HBG1, HBG2, OGG1 | SMN1; SMN2 1728/4885NPC1 3168/4885RAB9A 3751/4885 |
| US-20250052650-A1 | FLUOROGENIC CYANINE COMPOUNDS FOR DETECTING NUCLEIC ACIDS | HBG1, HBG2, OGG1 | SMN1; SMN2 1728/4885NPC1 3168/4885RAB9A 3751/4885 |
| US-12169166-B2 | Fluorogenic cyanine compounds for detecting nucleic acids | HBG1, HBG2, OGG1 | SMN1; SMN2 1728/4885NPC1 3168/4885RAB9A 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.