Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440227 | 0.87 | ALDH1A1 (0.40) | CNR2IRAK4ALDH1A1POLBHPGD | |
| SCHEMBL441653 | 0.87 | ALDH1A1 (0.43) | IRAK4ALDH1A1POLBHPGDBLM | |
| SCHEMBL1120023 | 0.84 | ALDH1A1 (0.34) | IRAK4ALDH1A1POLBHPGDBLM | |
| SCHEMBL14837946 | 0.80 | ALDH1A1 (0.36) | ALDH1A1POLBHPGDBLMHSD17B10 | |
| SCHEMBL1120079 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HPGDLMNARAB9AKMT2A | |
| SCHEMBL14837568 | 0.74 | ALDH1A1 (0.37) | ALDH1A1POLBHPGDBLMHSD17B10 | |
| SCHEMBL30404348 | 0.73 | TSHR (0.47) | CNR2ALDH1A1HPGDLMNARAB9A | |
| SCHEMBL1120218 | 0.72 | ALDH1A1 (0.35) | IRAK4ALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL15939786 | 0.71 | ALDH1A1 (0.37) | ALDH1A1POLBHPGDBLMHSD17B10 | |
| SCHEMBL15446675 | 0.71 | ALDH1A1 (0.43) | IRAK4ALDH1A1POLBHPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748420-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-8604040-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| EP-2576539-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2011147765-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | CNR2 1408/4885IRAK4 3410/4885ALDH1A1 1009/4885 |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | CNR2 1427/4885IRAK4 3478/4885ALDH1A1 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.