Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119900 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL14880226 | 0.77 | GAA (0.49) | HPGDPOLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29677 | 0.77 | CYP1A2 (0.34) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL13228438 | 0.77 | ALDH1A1 (0.35) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL1119901 | 0.77 | ALDH1A1 (0.35) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL29908189 | 0.77 | DRD4 (0.41) | ALDH1A1HPGDGAA | |
| SCHEMBL440227 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL18978979 | 0.75 | FAAH (0.36) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL18978790 | 0.75 | ALDH1A1 (0.33) | ALDH1A1HPGDPOLBBLMHSD17B10 | |
| SCHEMBL15939573 | 0.75 | TMIGD3 (0.37) | ALDH1A1HPGDKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228372-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228372-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | ARG1, ARG2, NOX3 | ALDH1A1 1122/4885HPGD 874/4885POLB 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.