Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 6/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402775 | 0.91 | USP10 (0.41) | USP10RXFP1LMNAMAPK1MAPT | |
| SCHEMBL1923430 | 0.90 | USP10 (0.52) | USP10MEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL1923423 | 0.84 | GAPDH (0.48) | USP10LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL1923540 | 0.81 | USP10 (0.45) | USP10RXFP1LMNAKMT2AMAPT | |
| SCHEMBL1923607 | 0.81 | CTSL (0.47) | USP10LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL1923492 | 0.81 | USP10 (0.53) | USP10RXFP1LMNAMEN1KMT2A | |
| SCHEMBL1923682 | 0.80 | USP10 (0.49) | USP10RXFP1LMNAMEN1KMT2A | |
| SCHEMBL27775353 | 0.79 | USP10 (0.51) | USP10RXFP1LMNAMAPTPOLB | |
| SCHEMBL1923811 | 0.78 | USP10 (0.45) | USP10LMNAMEN1KMT2AMAPT | |
| SCHEMBL1923845 | 0.78 | USP10 (0.48) | USP10MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064185-A1 | 1H-QUINOLIN-4-ONE COMPOUNDS, WITH AFFINITY FOR THE GABA RECEPTOR, PROCESSES, USES AND COMPOSITIONS | Ferrer Internacional, S.A. (ES) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008017710-A1 | 1H-QUINOLIN-4-ONE COMPOUNDS, WITH AFFINITY FOR THE GABA RECEPTOR, PROCESSES, USES AND COMPOSITIONS | FERRER INTERNACIONAL S.A. (ES) | 2008-02-14 | — | — | WO | disclosed |