SCHEMBL440845

SCHEMBL440845

O=C1C2CC3CC1CN(C3)C2

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466525 1.00 EPHX2 (0.36) EPHX2
SCHEMBL15466527 1.00 EPHX2 (0.36) EPHX2
SCHEMBL439944 1.00 EPHX2 (0.36) EPHX2
SCHEMBL22776055 1.00 EPHX2 (0.36) EPHX2
SCHEMBL2092396 0.97 EPHX2 (0.35) EPHX2
SCHEMBL15466425 0.74 CHRNB2 (0.31)
SCHEMBL3773537 0.72
SCHEMBL875052 0.69
SCHEMBL15466342 0.69 SMN1; SMN2 (0.34)
SCHEMBL8141299 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139891-B1 4-SUBSTITUTED AZAADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF ABBOTT LAB (US) 2012-09-05 EP claimed
US-20250236945-A1 Method of Implanting Atoms in a Substrate and Method of Forming a Quantum Register UNIVERSITAET ULM (DE) 2025-07-24 US disclosed
EP-4423326-A1 METHOD OF IMPLANTING ATOMS IN A SUBSTRATE AND METHOD OF FORMING A QUANTUM REGISTER SaxonQ GmbH (DE) 2024-09-04 EP disclosed
WO-2023072384-A1 METHOD OF IMPLANTING ATOMS IN A SUBSTRATE AND METHOD OF FORMING A QUANTUM REGISTER UNIVERSITÄT ULM (DE) 2023-05-04 WO disclosed
WO-2023073060-A1 METHOD OF IMPLANTING ATOMS IN A SUBSTRATE AND METHOD OF FORMING A QUANTUM REGISTER UNIVERSITAET ULM (DE) 2023-05-04 WO disclosed
CN-115215725-A Method for preparing lavender acetate and lavender alcohol 宋晓瑜 2022-10-21 CN disclosed
US-9983218-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2018-05-29 US disclosed
US-9983218-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2018-05-29 US disclosed
US-9983218-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2018-05-29 US disclosed
US-20180024144-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF ABBVIE INC. (US) 2018-01-25 US disclosed
EP-0652879-B1 1-AZAADAMANTANE DERIVATIVES AS 5-HT4 AGONISTS OR ANTAGONISTS AND/OR 5-HT3 ANTAGONISTS SEARLE & CO (US) 1999-04-14 EP disclosed
US-5840903-A 5-HT3 AND 5-HT4 AGONISTS AND ANTAGONISTS G. D. SEARLE & CO. (US) 1998-11-24 US disclosed
US-5643917-A GASTROINTESTINAL DISORDERS, 5HT ANTAGONISTS OR AGONISTS, COGNITION ACTIVATORS OR CNS DISORDERS G. D. SEARLE & CO. (US) 1997-07-01 US disclosed
US-5534521-A SEROTONIN ANTAGONISTS G. D. SEARLE & CO. (US) 1996-07-09 US disclosed
US-5521193-A SEROTONIN AGONISTS AND ANTAGONISTS G. D. SEARLE & CO. (US) 1996-05-28 US disclosed
EP-0652879-A1 1-AZAADAMANTANE DERIVATIVES AS 5-HT AGONISTS OR ANTAGONISTS G.D. SEARLE & CO. (US) 1995-05-17 EP disclosed
WO-1994002482-A1 1-AZAADAMANTANE DERIVATIVES AS 5-HT AGONISTS OR ANTAGONISTS G.D. SEARLE & CO. (US) 1994-02-03 WO disclosed
WO-1994000454-A1 BENZIMIDAZOLE COMPOUNDS G.D. SEARLE & CO. (US) 1994-01-06 WO disclosed
US-4816453-A N-heterocyclic derivatives of benzamides and their use in treating gastric and intestinal disorders BEECHAM GROUP, P.L.C. (GB) 1989-03-28 US disclosed
EP-0227215-A1 1-Azatricycloalkylbenzamides, process for their preparation, and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180024144-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF IDO1, IDO2, TPH1 EPHX2 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.