Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907147 | 1.00 | ALDH1A1 (0.72) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL29906119 | 0.90 | ALDH1A1 (0.72) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL21547326 | 0.90 | ALDH1A1 (0.72) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL28473708 | 0.90 | ALDH1A1 (0.83) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL30146601 | 0.89 | ALDH1A1 (0.62) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL15570727 | 0.88 | ALDH1A1 (0.69) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL2450851 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| Meradimate SCHEMBL8329573 | 0.85 | ALDH1A1 (0.98) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL21530854 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL21530852 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HPGDACLYNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465763-B2 | 3-hydroxychlormadinone acetate for the topical treatment of androgen-dependent skin diseases | RICHTER GEDEON NYRT. (HU) | 2013-06-18 | — | — | US | disclosed |
| US-20090318395-A1 | 3-HYDROXYCHLORMADINONE ACETATE FOR THE TOPICAL TREATMENT OF ANDROGEN-DEPENDENT SKIN DISEASES | GRUNENTHAL GMBH (DE) | 2009-12-24 | — | — | US | disclosed |