Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547326 | 1.00 | ALDH1A1 (0.72) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL15570727 | 0.91 | ALDH1A1 (0.69) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL4408464 | 0.90 | ALDH1A1 (0.72) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL2907147 | 0.90 | ALDH1A1 (0.72) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL28473708 | 0.90 | ALDH1A1 (0.83) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL15570725 | 0.90 | ALDH1A1 (0.65) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| Methacrylic Acid SCHEMBL31685164 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL21530852 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL21530854 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HPGDACLYNPSR1KDM4E | |
| SCHEMBL29410039 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HPGDACLYNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250120991-A1 | TOPICAL ANALGESIC | CONCEPT MATRIX SOLUTIONS (US) | 2025-04-17 | — | — | US | disclosed |
| US-12171774-B2 | Topical analgesic | CONCEPT MATRIX SOLUTIONS (US) | 2024-12-24 | — | — | US | disclosed |
| US-20220378812-A1 | TOPICAL ANALGESIC | CONCEPT MATRIX SOLUTIONS (US) | 2022-12-01 | — | — | US | disclosed |
| US-11439654-B2 | Topical analgesic | CONCEPT MATRIX SOLUTIONS | 2022-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11439654-B2 | Topical analgesic | TRPV1, CNR2, FAAH | ALDH1A1 1140/4885HPGD 109/4885ACLY 3427/4885 |
| US-20220378812-A1 | TOPICAL ANALGESIC | TRPV1, CNR2, FAAH | ALDH1A1 1140/4885HPGD 109/4885ACLY 3427/4885 |
| US-12171774-B2 | Topical analgesic | TRPV1, CNR2, FAAH | ALDH1A1 1140/4885HPGD 109/4885ACLY 3427/4885 |
| US-20250120991-A1 | TOPICAL ANALGESIC | TRPV1, CNR2, FAAH | ALDH1A1 1140/4885HPGD 109/4885ACLY 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.