Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177303 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| Butamifos SCHEMBL54426 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| Butamifos SCHEMBL29889547 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL29776928 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL8567473 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL10907764 | 0.75 | CYP3A4 (0.44) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL8567480 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL8567477 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL7775360 | 0.72 | TSHR (0.56) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR | |
| SCHEMBL11046676 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3300590-B1 | DOUBLING OF CHROMOSOMES IN HAPLOID MAIZE EMBRYOS | PIONEER HI BRED INT (US) | 2020-05-27 | — | — | EP | disclosed |
| EP-3300590-A1 | DOUBLING OF CHROMOSOMES IN HAPLOID MAIZE EMBRYOS | Pioneer Hi-Bred International Inc. (US) | 2018-04-04 | — | — | EP | disclosed |
| EP-2111747-A2 | Doubling of chomosomes in haploid embryos | Pioneer Hi-Bred International Inc. (US) | 2009-10-28 | — | — | EP | disclosed |