Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL8330357 | 0.87 | TSHR (0.53) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL3428898 | 0.82 | TSHR (0.51) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL1684281 | 0.81 | CYP3A4 (0.50) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL29790901 | 0.81 | CYP3A4 (0.50) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL7775199 | 0.81 | TSHR (0.46) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| Lithium Ion SCHEMBL8329179 | 0.81 | TSHR (0.46) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL425259 | 0.80 | TSHR (0.62) | TSHRCYP3A4ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL9324968 | 0.79 | TSHR (0.47) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL29776928 | 0.77 | ALDH1A1 (0.52) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL10619771 | 0.77 | ALDH1A1 (0.62) | TSHRCYP3A4ALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001507707-A | — | — | 2001-06-12 | — | — | JP | claimed |
| EP-0948503-A1 | PREPARATION OF CYANOPHOSPHONATES FROM PHOSPHATES AND CYANIDE | MONSANTO COMPANY (US) | 1999-10-13 | — | — | EP | claimed |
| US-5861525-A | Method for preparing cyanophosphonate derivatives from phosphate esters and cyanide | MONSANTO COMPANY (US) | 1999-01-19 | — | — | US | claimed |
| WO-1998029424-A1 | PREPARATION OF CYANOPHOSPHONATES FROM PHOSPHATES AND CYANIDE | MONSANTO COMPANY (US) | 1998-07-09 | — | — | WO | claimed |
| EP-0948503-A1 | PREPARATION OF CYANOPHOSPHONATES FROM PHOSPHATES AND CYANIDE | MONSANTO COMPANY (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5861525-A | Method for preparing cyanophosphonate derivatives from phosphate esters and cyanide | MONSANTO COMPANY (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1998029424-A1 | PREPARATION OF CYANOPHOSPHONATES FROM PHOSPHATES AND CYANIDE | MONSANTO COMPANY (US) | 1998-07-09 | — | — | WO | disclosed |