SCHEMBL4408716

SCHEMBL4408716

Nc1ccc(C2(c3ccc(N)cc3Oc3ccccc3)C3CC4CC(C3)CC2C4)c(Oc2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
MAOA P21397 1/20 0.40
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
KDM1A O60341 3/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NLRP3 Q96P20 1/20 0.37
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MITF O75030 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709020 0.85 ALDH1A1 (0.36) MAOBMEN1KMT2ANPC1RAB9A
SCHEMBL2708157 0.82 NCOA1 (0.47) MAOBMAOANCOA1NCOA3KDM1A
SCHEMBL4408351 0.81 GRIN2D (0.39) MAOBMAOANCOA1NCOA3KDM1A
SCHEMBL4418505 0.74 KDM1A (0.33) MAOAKDM1ACYP3A4CYP1A2CYP2C9
SCHEMBL4418788 0.74 KDM1A (0.33) MAOAKDM1AMEN1KMT2AMAPT
SCHEMBL7165822 0.71 GLA (0.36) MAOACYP3A4GAA
SCHEMBL5441304 0.70 MAOA (0.58) MAOBMAOANCOA1NCOA3MEN1
SCHEMBL2709017 0.70 GAA (0.36) NCOA1NCOA3MEN1KMT2ACYP3A4
SCHEMBL2706943 0.70 GAA (0.38) NCOA1NCOA3MEN1KMT2AMAPT
SCHEMBL3794430 0.70 NCOA1 (0.68) MAOBMAOANCOA1NCOA3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed