SCHEMBL4408743

SCHEMBL4408743

COC(=O)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.67
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
RAB9A P51151 5/20 0.58
L3MBTL1 Q9Y468 3/20 0.58
MAPT P10636 3/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
ROCK2 O75116 1/20 0.55
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8364599 0.95 TSHR (0.60) TSHRMEN1KMT2ARAB9AL3MBTL1
SCHEMBL23128710 0.90 PTPN11 (0.56) TSHRMEN1KMT2ARAB9AL3MBTL1
SCHEMBL1222150 0.87 TSHR (0.64) TSHRMEN1KMT2ARAB9AL3MBTL1
SCHEMBL18390946 0.85 TDP1 (0.77) TSHRMEN1KMT2ARAB9AMAPT
SCHEMBL11672937 0.84 LMNA (0.46) TSHRMEN1KMT2ARAB9AL3MBTL1
Methyl Benzoate SCHEMBL28249321 0.83 TSHR (0.95) TSHRMEN1KMT2ARAB9AL3MBTL1
Benzene SCHEMBL28351738 0.83 TSHR (0.85) TSHRMEN1KMT2ARAB9AL3MBTL1
SCHEMBL4408660 0.83 NOTUM (0.54) TSHRMEN1KMT2ARAB9AMAPT
SCHEMBL14340699 0.83 KMT2A (0.49) TSHRMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL12761817 0.83 ALOX15 (0.50) TSHRMEN1KMT2ARAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057663-B Triphenylamine derivative with mechanochromatic characteristic and preparation method and application thereof 吉林大学 2023-09-08 CN claimed
CN-114057663-A Triphenylamine derivative with mechanochromic characteristic and preparation method and application thereof 吉林大学 2022-02-18 CN claimed
CN-112939888-A Star-shaped D-A type conjugated molecule and synthetic method and application thereof 吉林大学 2021-06-11 CN claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
US-20250014774-A1 PEROVSKITE-ORGANIC CHROMOPHORE BASED X-RAY IMAGINING SCINTILLATOR KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2025-01-09 US disclosed
CN-114057663-B Triphenylamine derivative with mechanochromatic characteristic and preparation method and application thereof 吉林大学 2023-09-08 CN disclosed
WO-2023073662-A1 PEROVSKITE-ORGANIC CHROMOPHORE BASED X-RAY IMAGINING SCINTILLATOR KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2023-05-04 WO disclosed
CN-114057663-A Triphenylamine derivative with mechanochromic characteristic and preparation method and application thereof 吉林大学 2022-02-18 CN disclosed
CN-112939888-A Star-shaped D-A type conjugated molecule and synthetic method and application thereof 吉林大学 2021-06-11 CN disclosed
WO-2020044213-A1 DIPHENYLAMINO-METHYLENE MALONONITRILE BASED COMPOUNDS AS FLUORESCENCE PROBES UNIVERSITY OF HYDERABAD (IN) 2020-03-05 WO disclosed
WO-2020044213-A1 DIPHENYLAMINO-METHYLENE MALONONITRILE BASED COMPOUNDS AS FLUORESCENCE PROBES UNIVERSITY OF HYDERABAD (IN) 2020-03-05 WO disclosed
US-8664400-B2 Triphenylamine derivatives useful as fluorophores in biology, in particular for two-photon microscopy CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-03-04 US disclosed
EP-1313560-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2003-05-28 EP disclosed
US-6562989-B2 Bicyclopentyl iron ligand and transition metal catalyst YALE UNIVERSITY 2003-05-13 US disclosed
US-20030008768-A1 Catalyst for aromatic C-O, C-N, and C-C bond formation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-09 US disclosed
WO-2002011883-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2002-02-14 WO disclosed
US-5080989-A Polycarbonate, solvent resistance EASTMAN KODAK COMPANY (US) 1992-01-14 US disclosed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed
US-4018607-A Crystalline organic pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed
US-4018606-A Organic azo pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed