SCHEMBL4408935

SCHEMBL4408935

CCCCCCn1nnc(Cl)n1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.43
KMT2A Q03164 1/20 0.40
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408850 0.98 KMT2A (0.41) TRPV1KMT2AMAPK1
SCHEMBL4413912 0.92 MAPK1 (0.43) TRPV1KMT2AMAPK1
SCHEMBL4413802 0.78 TRPV1 (0.43) TRPV1KMT2A
SCHEMBL4404362 0.78 TRPV1 (0.43) TRPV1KMT2A
SCHEMBL4405330 0.77 TRPV1 (0.43) TRPV1KMT2A
SCHEMBL9872140 0.77 ALDH1A1 (0.49) TRPV1KMT2A
SCHEMBL9872644 0.77 ALDH1A1 (0.49) TRPV1KMT2A
SCHEMBL8962480 0.77 ALDH1A1 (0.49) TRPV1KMT2A
SCHEMBL9872505 0.77 ALDH1A1 (0.49) TRPV1KMT2A
SCHEMBL4414761 0.77 TRPV1 (0.43) TRPV1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed