Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506947 | 0.81 | NPC1 (0.37) | NPC1RAB9AHPGDKDM4EMAPT | |
| SCHEMBL4408852 | 0.81 | ABCG2 (0.46) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL4404185 | 0.81 | ABCG2 (0.46) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL4406033 | 0.78 | ABCG2 (0.44) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL4408406 | 0.78 | ABCG2 (0.44) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL54820 | 0.74 | ABCG2 (0.50) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL4412042 | 0.73 | HPGD (0.53) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL513472 | 0.72 | HPGD (0.42) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4410795 | 0.71 | NPC1 (0.55) | ABCG2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL4187230 | 0.69 | ABCG2 (0.50) | ABCG2NPC1RAB9AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |