Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407303 | 0.80 | HPGD (0.57) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL512253 | 0.78 | HPGD (0.63) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL4409279 | 0.77 | HPGD (0.54) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL513770 | 0.77 | HPGD (0.57) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL4405944 | 0.76 | HPGD (0.53) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL4409289 | 0.75 | HPGD (0.55) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL4412019 | 0.75 | HPGD (0.51) | HPGDABCG2NPC1RAB9AMAPT | |
| SCHEMBL4412239 | 0.73 | RAB9A (0.54) | NPC1RAB9ALMNAALDH1A1GRN | |
| SCHEMBL4414660 | 0.73 | HPGD (0.50) | HPGDABCG2NPC1RAB9AABCB1 | |
| SCHEMBL4408946 | 0.73 | ABCG2 (0.46) | HPGDABCG2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |