Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408852 | 0.85 | ABCG2 (0.46) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4408946 | 0.78 | ABCG2 (0.46) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4404185 | 0.78 | ABCG2 (0.46) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4408406 | 0.75 | ABCG2 (0.44) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4410795 | 0.72 | NPC1 (0.55) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4409073 | 0.71 | RAB9A (0.54) | NPC1RAB9A | |
| SCHEMBL31375500 | 0.68 | NPC1 (0.45) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL54820 | 0.67 | ABCG2 (0.50) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4406572 | 0.67 | ABCG2 (0.50) | ABCG2NPC1RAB9AHPGDMAPT | |
| SCHEMBL4407724 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |