Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 6/20 | 0.32 |
| ▸ | NOS1 | P29475 | 6/20 | 0.32 |
| ▸ | NOS2 | P35228 | 6/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188454 | 0.76 | HTR6 (0.38) | CDK2NUDT1HRH4 | |
| SCHEMBL3209557 | 0.74 | HTR6 (0.36) | CDK2HRH4 | |
| SCHEMBL605651 | 0.72 | HRH3 (0.65) | HRH4 | |
| SCHEMBL14616991 | 0.72 | NPC1 (0.31) | — | |
| SCHEMBL4259972 | 0.72 | NPC1 (0.38) | ADORA2AKDM4EALDH1A1 | |
| SCHEMBL4410427 | 0.70 | DHFR (0.33) | HRH4 | |
| SCHEMBL603031 | 0.70 | HRH4 (0.69) | HRH4 | |
| SCHEMBL604460 | 0.70 | HRH3 (0.44) | NUDT1HRH4 | |
| SCHEMBL603528 | 0.68 | HRH3 (0.67) | HRH4 | |
| SCHEMBL24309619 | 0.67 | HRH4 (0.59) | CDK2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077608-A1 | 2 -AMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS | PALAU PHARMA, S. A. (ES) | 2009-06-25 | — | — | WO | disclosed |