Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404245 | 0.94 | ALDH1A1 (0.41) | ALDH1A1HTR1AKMT2AMEN1HTT | |
| SCHEMBL4409151 | 0.92 | ALDH1A1 (0.40) | ALDH1A1LMNA | |
| SCHEMBL4408138 | 0.87 | ALDH1A1 (0.45) | ALDH1A1HTR1AKMT2AMEN1LMNA | |
| SCHEMBL4406557 | 0.86 | KMT2A (0.42) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4407174 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL4403827 | 0.84 | SLC9A1 (0.41) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL7304012 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HTR1AKMT2AMEN1LMNA | |
| SCHEMBL4403652 | 0.82 | SLC9A1 (0.42) | ALDH1A1KMT2AMEN1HTTCYP2C19 | |
| SCHEMBL4404421 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL4404533 | 0.81 | CNR2 (0.47) | ALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2007139818-A2 | PHARMACOLOGICAL TREATMENT OF COGNITIVE IMPAIRMENT | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-12-06 | — | — | WO | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |