SCHEMBL4409195

SCHEMBL4409195

Cc1cccc(C2=NOC(=O)/C2=C/C=C/c2ccc(N(C)C)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
PKM P14618 3/20 0.58
MAPK1 P28482 3/20 0.58
LMNA P02545 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
KDM4E B2RXH2 2/20 0.58
PLIN1 O60240 1/20 0.58
POLB P06746 1/20 0.58
RAB9A P51151 1/20 0.58
PLIN5 Q00G26 1/20 0.58
ABHD5 Q8WTS1 1/20 0.58
APP P05067 12/20 0.46
METAP1 P53582 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
OPRK1 P41145 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9970455 0.87 MAPT (0.67) MAPTMEN1KMT2APKMMAPK1
SCHEMBL124423 0.87 MAPT (0.67) MAPTMEN1KMT2APKMMAPK1
SCHEMBL14305631 0.83 KMT2A (0.61) MAPTMEN1KMT2APKMMAPK1
SCHEMBL4900562 0.83 KMT2A (0.61) MAPTMEN1KMT2APKMMAPK1
SCHEMBL4900571 0.83 KMT2A (0.61) MAPTMEN1KMT2APKMMAPK1
SCHEMBL13383119 0.74 KMT2A (0.58) MAPTMEN1KMT2APKMMAPK1
SCHEMBL29518097 0.73 KMT2A (1.00) MAPTMEN1KMT2APKMMAPK1
SCHEMBL18193291 0.72 KMT2A (0.73) MAPTMEN1KMT2APKMMAPK1
SCHEMBL12691236 0.71 KMT2A (0.58) MAPTMEN1KMT2APKMMAPK1
SCHEMBL10871711 0.70 KMT2A (0.40) MAPTMEN1KMT2APKMMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261270-B1 Polymer, producing method thereof, and photorefractive composition NITTO DENKO CORP (JP) 2012-05-09 EP disclosed