SCHEMBL4900562

SCHEMBL4900562

CN(C)c1ccc(/C=C/C=C/C=C2/C(=O)ON=C2c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.61
MEN1 O00255 8/20 0.61
MAPT P10636 7/20 0.61
PKM P14618 3/20 0.61
MAPK1 P28482 3/20 0.61
LMNA P02545 3/20 0.61
ALDH1A1 P00352 3/20 0.61
NPSR1 Q6W5P4 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
KDM4E B2RXH2 1/20 0.61
PLIN1 O60240 1/20 0.61
POLB P06746 1/20 0.61
RAB9A P51151 1/20 0.61
PLIN5 Q00G26 1/20 0.61
ABHD5 Q8WTS1 1/20 0.61
APP P05067 7/20 0.57
AR P10275 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
OPRK1 P41145 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4900571 1.00 KMT2A (0.61) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL14305631 1.00 KMT2A (0.61) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL124423 0.95 MAPT (0.67) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL9970455 0.95 MAPT (0.67) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL4409195 0.83 MAPT (0.58) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL18193291 0.82 KMT2A (0.73) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL13383119 0.81 KMT2A (0.58) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL12691236 0.78 KMT2A (0.58) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL29518097 0.76 KMT2A (1.00) KMT2AMEN1MAPTPKMMAPK1
SCHEMBL4440955 0.72 APP (0.83) KMT2AMEN1MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080002329-A1 High Dielectric, Non-Linear Capacitor POHM ARTHUR V 2008-01-03 US disclosed
US-20070206342-A1 High Dielectric, Non-Linear Nano-Capacitor NANO-ELECTROCHEM, INC. 2007-09-06 US disclosed
US-20060291278-A1 Nano-Reflectors for Thin, Flat Display Devices NANO-ELECTROCHEM, INC. (US) 2006-12-28 US disclosed