Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.67 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970455 | 1.00 | MAPT (0.67) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL4900571 | 0.95 | KMT2A (0.61) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL4900562 | 0.95 | KMT2A (0.61) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL14305631 | 0.95 | KMT2A (0.61) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL4409195 | 0.87 | MAPT (0.58) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL13383119 | 0.85 | KMT2A (0.58) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL18193291 | 0.84 | KMT2A (0.73) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL12691236 | 0.82 | KMT2A (0.58) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL29518097 | 0.81 | KMT2A (1.00) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL1454822 | 0.73 | APP (0.69) | MAPTKMT2AMEN1PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | MAPT 2242/4885KMT2A 3041/4885MEN1 4480/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | MAPT 2173/4885KMT2A 2961/4885MEN1 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.