SCHEMBL4409368

SCHEMBL4409368

CC/C(=C(/C)C(=O)O)N(C(C)OC)C(C)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3279128 0.80 FFAR3 (0.32)
SCHEMBL20377697 0.80 FFAR3 (0.32)
SCHEMBL10814074 0.79 FFAR3 (0.31)
SCHEMBL4615318 0.69
SCHEMBL44909 0.69 ALDH1A1 (0.36)
SCHEMBL109778 0.69 ALDH1A1 (0.36)
Acetic Acid SCHEMBL6238297 0.67 FFAR3 (0.35)
SCHEMBL119068 0.67 LMNA (0.36)
Hydrochloric Acid SCHEMBL5177423 0.67 ALDH1A1 (0.35)
SCHEMBL1650860 0.67 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751407-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP claimed
EP-0751405-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP claimed
EP-0751404-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP claimed
US-5391669-A Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers HYDRON LIMITED (GB) 1995-02-21 US claimed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US claimed
EP-1286823-B1 OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME COOPERVISION INT HOLDING CO LP (BB) 2009-06-17 EP disclosed
US-7262232-B2 Ophthalmic lenses and compositions and methods for producing same COOPERVISION, INC. (US) 2007-08-28 US disclosed
US-6992118-B2 Ophthalmic lenses and compositions and methods for producing same COOPER VISION INC. (US) 2006-01-31 US disclosed
US-20050191335-A1 Ophthalmic lenses and compositions and methods for producing same COOPERVISION INC. (US) 2005-09-01 US disclosed
US-20040046932-A1 Ophthalmic lenses and compositions and methods for producing same OCULAR SCIENCES, INC. 2004-03-11 US disclosed
US-6617373-B2 First crosslinked polymer material which is water swellable, and a second polymeric material physically imobilized by the first OCULAR SCIENCES, INC. 2003-09-09 US disclosed
US-20020091175-A1 Ophthalmic lenses and compositions and methods for producing same OCULAR SCIENCES, INC. 2002-07-11 US disclosed
EP-0751407-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP disclosed
EP-0751406-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP disclosed
EP-0751405-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP disclosed
US-5391669-A Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers HYDRON LIMITED (GB) 1995-02-21 US disclosed
EP-0563299-A4 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM CESKOSLOVENSKA AKADEMIE VED (CS) 1994-07-20 EP disclosed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US disclosed
EP-0563299-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM Hydron Limited (GB) 1993-10-06 EP disclosed
WO-1992011301-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM ALLERGAN, INC. (US) 1992-07-09 WO disclosed