SCHEMBL440944

SCHEMBL440944

Clc1ccc(Cl)c(-c2cc(Cl)ccc2Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.61
HTR2B P41595 1/20 0.54
PDE4D Q08499 1/20 0.54
ALDH1A1 P00352 4/20 0.52
TSHR P16473 4/20 0.52
CYP3A4 P08684 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
S100A4 P26447 1/20 0.50
PTPN11 Q06124 1/20 0.50
IDO1 P14902 1/20 0.50
RXFP1 Q9HBX9 1/20 0.48
MAPT P10636 1/20 0.47
PTPN1 P18031 1/20 0.45
PPOX P50336 1/20 0.44
AHR P35869 1/20 0.44
LMNA P02545 1/20 0.44
CYP2A6 P11509 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364307 1.00 TP53 (0.61) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL811509 0.89 AHR (0.63) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL29776961 0.89 AHR (0.63) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL30336978 0.89 TP53 (0.57) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL4446831 0.89 TP53 (0.57) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL29363845 0.89 AHR (0.63) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL29983105 0.87 PTPN1 (0.56) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL29416774 0.87 PTPN1 (0.56) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL381603 0.87 PTPN1 (0.56) TP53HTR2BPDE4DALDH1A1TSHR
SCHEMBL9732124 0.84 TSHR (0.58) TP53HTR2BPDE4DALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119619489-A Homogeneous enzyme immunoassay system based on click chemistry coupling technology and preparation method and application thereof 苏州博源医疗科技有限公司 2025-03-14 CN claimed
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
CN-118389643-A Biological sensing environment detection platform for detecting small molecules sensitively based on fluorescent RNA aptamer logic gate 湘潭大学 2024-07-26 CN claimed
EP-4160211-A1 DETECTING THE EXPOSURE OF A SUBJECT TO A THYROID DISRUPTING CHEMICAL, EVEN BEFORE HYPOTHYROIDISM APPEARS Moreno Navarro, José Carlos (ES) 2023-04-05 EP claimed
CN-113773998-B PCBs composite degrading microbial inoculum and application thereof 广东海洋大学 2023-03-21 CN claimed
CN-111308003-B Method for simultaneously detecting diisopropylnaphthalenes, polychlorinated biphenyls, phthalate compounds and photoinitiator 福建中烟工业有限责任公司 2022-11-08 CN claimed
CN-115248258-A Preparation and detection method of to-be-detected sample of polychlorinated biphenyl in packaging material 湖南中烟工业有限责任公司 2022-10-28 CN claimed
US-20220326160-A1 METHOD FOR TRAPPING MOLECULE WITH OPTICAL FIBER TWEEZERS BASED ON PHASE TRANSITION AND CRYSTALLIZATION AND METHOD FOR DETECTING RAMAN SPECTRUM OF PERSISTENT ORGANIC POLLUTANT DONGGUAN UNIVERSITY OF TECHNOLOGY (CN) 2022-10-13 US claimed
CN-111665313-B Method for determining polychlorinated biphenyl compounds in aquatic products 孟祥龙 2022-10-11 CN claimed
US-11448599-B1 Method for trapping molecule with optical fiber tweezers based on phase transition and crystallization and method for detecting raman spectrum of persistent organic pollutant DONGGUAN UNIVERSITY OF TECHNOLOGY (CN) 2022-09-20 US claimed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO claimed
US-20060281961-A1 Functional transition metal silicates KANUMURU RAHUL RAJU (IN) 2006-12-14 US claimed
US-6544773-B1 For degrading different congeners namely coplanar, sterically hindered and other chlorobiphenyls COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-04-08 US claimed
US-20030054538-A1 Microbial process for degradation of PCBs in clophen A-50 using a novel marine microorganism, pseudomonas CH07 SARKAR ANUPAM (IN) 2003-03-20 US claimed
US-5629170-A SCREENING MICROORGANISM-CONTAINING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1997-05-13 US claimed
EP-0558997-B1 Process for reducing the halogen-content of polyhalogenated aromatics BAYER AG (DE) 1995-11-22 EP claimed
US-5292975-A Platinum metal catalyst BAYER AKTIENGESELLSCHAFT (DE) 1994-03-08 US claimed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
US-4200698-A BROMO BUTADIENE POLYMER, CHLOROCARBON, EPOXIDIZED CYCLOOLEFIN, POLYAMINE OR POLYAMIDE MICAFIL, AG (CH) 1980-04-29 US claimed
US-4067990-A SOLUTION OF A PHENYL N-METHYL CARBAMATE AIRWICK INDUSTRIES, INC. (US) 1978-01-10 US claimed