SCHEMBL381603

SCHEMBL381603

Clc1ccc(Cl)c(-c2ccccc2Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.56
S100A4 P26447 1/20 0.50
CYP2A6 P11509 2/20 0.48
TP53 P04637 2/20 0.48
HTR2B P41595 1/20 0.45
PDE4D Q08499 1/20 0.45
DPP4 P27487 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.45
PLA2G7 Q13093 1/20 0.44
GPR3 P46089 1/20 0.43
CNR2 P34972 1/20 0.43
TSHR P16473 3/20 0.43
LMNA P02545 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416774 1.00 PTPN1 (0.56) PTPN1S100A4CYP2A6TP53HTR2B
SCHEMBL29983105 1.00 PTPN1 (0.56) PTPN1S100A4CYP2A6TP53HTR2B
SCHEMBL29364307 0.87 TP53 (0.61) PTPN1S100A4CYP2A6TP53HTR2B
SCHEMBL440944 0.87 TP53 (0.61) PTPN1S100A4CYP2A6TP53HTR2B
SCHEMBL2934558 0.85 AHR (0.52) PTPN1S100A4CYP2A6TP53DPP4
SCHEMBL29416163 0.85 AHR (0.52) PTPN1S100A4CYP2A6TP53DPP4
SCHEMBL4450231 0.84 P2RX7 (0.44) PTPN1S100A4CYP2A6TP53HTR2B
SCHEMBL23609918 0.82 S100A4 (0.48) PTPN1S100A4CYP2A6DPP4SMN1; SMN2
SCHEMBL5004328 0.82 PTPN1 (0.50) PTPN1S100A4CYP2A6PDE4DDPP4
SCHEMBL10592032 0.82 PLA2G7 (0.47) PTPN1S100A4TP53HTR2BPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
CN-118639436-A Evaporation-driven power generation fabric and preparation method thereof 武汉纺织大学 2024-09-13 CN claimed
CN-115957617-A Dealkalized refining agent and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957592-A Dealkalization refining agent, preparation method thereof and application thereof in dealkalization of impurities from dry gas 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-218274022-U Soft shielding type automotive wiring harness 徐州市银铃新能源科技有限公司 2023-01-10 CN claimed
CN-111308003-B Method for simultaneously detecting diisopropylnaphthalenes, polychlorinated biphenyls, phthalate compounds and photoinitiator 福建中烟工业有限责任公司 2022-11-08 CN claimed
CN-115248258-A Preparation and detection method of to-be-detected sample of polychlorinated biphenyl in packaging material 湖南中烟工业有限责任公司 2022-10-28 CN claimed
CN-217010624-U Liquid-cooled motor and vehicle 江苏爱玛车业科技有限公司 2022-07-19 CN claimed
CN-114196618-A Exposure system of organic flame retardant to human respiratory tract cells and preparation method and application thereof 广东工业大学 2022-03-18 CN claimed
CN-113773998-A PCBs composite degrading microbial inoculum and application thereof 广东海洋大学 2021-12-10 CN claimed
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2002-09-19 US claimed
US-6380454-B1 DISTILLATION; SUPPLYING SODIUM; DECHLORINATION BY SALT FORMATION CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2002-04-30 US claimed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP claimed
EP-0503831-B1 Destruction of polychlorinated biphenyls ONTARIO HYDRO (CA) 1997-09-17 EP claimed
EP-0503831-A1 Destruction of polychlorinated biphenyls ONTARIO HYDRO (CA) 1992-09-16 EP claimed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
US-4357213-A Method of recovery of liquid chlorine derivatives of hydrocarbons MANTULO ALEXANDR P 1982-11-02 US claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed
US-4200698-A BROMO BUTADIENE POLYMER, CHLOROCARBON, EPOXIDIZED CYCLOOLEFIN, POLYAMINE OR POLYAMIDE MICAFIL, AG (CH) 1980-04-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME AHR, ARNT, TRPA1 PTPN1 4604/4885S100A4 4550/4885CYP2A6 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.