Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361183 | 0.83 | MEN1 (0.44) | TP53MAPTMEN1KMT2AKDM4E | |
| SCHEMBL662385 | 0.83 | MEN1 (0.44) | TP53MAPTMEN1KMT2AKDM4E | |
| SCHEMBL662975 | 0.82 | LMNA (0.48) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2951129 | 0.81 | LMNA (0.43) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1665637 | 0.81 | LMNA (0.42) | TP53MAPTSMN1; SMN2KDM4ETSHR | |
| SCHEMBL2951145 | 0.81 | GLA (0.48) | TP53KDM4E | |
| SCHEMBL661009 | 0.80 | ALDH1A1 (0.38) | TP53MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2954311 | 0.80 | LMNA (0.48) | TP53MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17938020 | 0.79 | KDM4E (0.47) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13238348 | 0.78 | ALDH1A1 (0.41) | TP53MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |