Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 7/20 | 0.46 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411036 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ERAP2 | |
| SCHEMBL13596841 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ERAP2 | |
| Hydrochloric Acid SCHEMBL11331994 | 0.98 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ERAP2 | |
| Bromide SCHEMBL7280488 | 0.98 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ERAP2 | |
| Hydrochloric Acid SCHEMBL11168287 | 0.94 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ERAP2 | |
| Trifluoroacetic Acid SCHEMBL9508365 | 0.91 | DPP4 (0.54) | DPP4DPP8DPP9DPP7ERAP2 | |
| SCHEMBL30729290 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3052901 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL10056816 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30567640 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | claimed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | claimed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | claimed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | claimed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | claimed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | claimed |
| US-7638638-B2 | Dipeptidyl peptidase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| EP-1625122-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | Takeda San Diego, Inc. (US) | 2006-02-15 | — | — | EP | disclosed |
| US-20040254226-A1 | Dipeptidyl peptidase inhibitors | SYRRX, INC. | 2004-12-16 | — | — | US | disclosed |
| WO-2004103993-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | disclosed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | disclosed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | disclosed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254226-A1 | Dipeptidyl peptidase inhibitors | DPP3, DPP4, DPP7 | DPP4 2/4885DPP8 5/4885DPP9 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.