Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | PEPD | P12955 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29802195 | 0.91 | DPP4 (0.55) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL4409965 | 0.91 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ERAP2 | |
| SCHEMBL13596841 | 0.91 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ERAP2 | |
| SCHEMBL4411036 | 0.91 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ERAP2 | |
| Hydrochloric Acid SCHEMBL11331994 | 0.90 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ERAP2 | |
| Bromide SCHEMBL7280488 | 0.90 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ERAP2 | |
| Trifluoroacetic Acid SCHEMBL31376322 | 0.85 | DPP4 (0.49) | DPP4DPP8DPP9DPP7ERAP2 | |
| Trifluoroacetic Acid SCHEMBL26616483 | 0.85 | DPP4 (0.49) | DPP4DPP8DPP9DPP7ERAP2 | |
| Hydrochloric Acid SCHEMBL11168287 | 0.85 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ERAP2 | |
| SCHEMBL3052901 | 0.83 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316218-B1 | L-PROLINE DERIVATIVES, THEIR PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | EKITA Investments N.V. (NA) | 1993-09-15 | — | — | EP | disclosed |
| US-5212158-A | Nootropic agents | INORGAN SA RECHERCHE & DEVELOPPEMENT PHARMACEUTIQUES, CAS (CH) | 1993-05-18 | — | — | US | disclosed |
| EP-0316218-A1 | L-proline derivatives, their preparation and biological applications thereof | EKITA Investments N.V. (NA) | 1989-05-17 | — | — | EP | disclosed |