Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586170 | 0.95 | STAT3 (0.44) | STAT3STAT1 | |
| SCHEMBL5585185 | 0.88 | STAT3 (0.45) | STAT3STAT1 | |
| SCHEMBL14867477 | 0.88 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL5533945 | 0.88 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL460386 | 0.85 | STAT3 (0.47) | STAT3STAT1 | |
| SCHEMBL7867113 | 0.84 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL9450931 | 0.83 | STAT3 (0.46) | STAT3STAT1 | |
| SCHEMBL4429826 | 0.82 | STAT3 (0.45) | STAT3STAT1 | |
| SCHEMBL1944649 | 0.82 | STAT3 (0.45) | STAT3STAT1 | |
| SCHEMBL5586168 | 0.82 | STAT3 (0.36) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521551-B2 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. | 2008-11-06 | — | — | US | disclosed |
| US-6849730-B2 | Methods of making porphyrins and related compounds with Lewis acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-02-01 | — | — | US | disclosed |
| US-20050020560-A1 | Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | disclosed |
| US-6794505-B1 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2004-09-21 | — | — | US | disclosed |
| US-20030096978-A1 | Methods of making porphyrins and related compounds with Lewis acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | disclosed |
| WO-2003027066-A2 | METHODS OF MAKING PORPHYRINS AND RELATED COMPOUNDS WITH LEWIS ACID | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2001074818-A1 | CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | PPOX, HMBS, DDT | STAT3 3696/4885STAT1 3561/4885 |
| US-20030096978-A1 | Methods of making porphyrins and related compounds with Lewis acids | DDT, LIG3, SHARPIN | STAT3 3690/4885STAT1 4534/4885 |
| US-20050020560-A1 | Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy | PPOX, HMBS, DDT | STAT3 3916/4885STAT1 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.