Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884918 | 0.92 | NR3C1 (0.62) | NR3C1 | |
| SCHEMBL3972292 | 0.86 | NR3C1 (0.53) | NR3C1MAPTTDP1L3MBTL1 | |
| SCHEMBL476759 | 0.85 | NR3C1 (0.71) | NR3C1 | |
| SCHEMBL3973080 | 0.85 | NR3C1 (0.68) | NR3C1 | |
| SCHEMBL3975510 | 0.84 | NR3C1 (0.57) | NR3C1 | |
| SCHEMBL13884670 | 0.84 | NR3C1 (0.61) | NR3C1 | |
| SCHEMBL13885528 | 0.84 | NR3C1 (0.59) | NR3C1 | |
| SCHEMBL13885359 | 0.83 | NR3C1 (0.65) | NR3C1 | |
| SCHEMBL13884722 | 0.83 | NR3C1 (0.52) | NR3C1MAPT | |
| SCHEMBL4407495 | 0.83 | NR3C1 (0.56) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050243-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050243-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |