Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 3/20 | 0.48 |
| ▸ | STAMBP | O95630 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671823 | 0.84 | HPGDS (0.72) | HPGDSPSMD14STAMBPHPGDMEN1 | |
| SCHEMBL4721861 | 0.84 | HPGDS (0.64) | HPGDSPSMD14NPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6086439 | 0.83 | HPGDS (0.71) | HPGDSPSMD14STAMBPHPGDMEN1 | |
| SCHEMBL2200731 | 0.83 | HPGDS (0.75) | HPGDSPSMD14STAMBPHPGDMEN1 | |
| SCHEMBL8614022 | 0.83 | HPGDS (0.71) | HPGDSPSMD14STAMBPMEN1KMT2A | |
| SCHEMBL18987846 | 0.82 | HPGDS (0.62) | HPGDSPSMD14STAMBPHPGDMEN1 | |
| SCHEMBL4145910 | 0.81 | HPGDS (0.67) | HPGDSPSMD14STAMBPMEN1KMT2A | |
| SCHEMBL27976330 | 0.81 | KMT2A (0.52) | HPGDSNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9360729 | 0.80 | MEN1 (0.49) | HPGDSNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL19020755 | 0.77 | HPGDS (0.56) | HPGDSPSMD14HPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |