Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.71 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.61 |
| ▸ | STAMBP | O95630 | 3/20 | 0.61 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.61 |
| ▸ | PARP1 | P09874 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671823 | 0.87 | HPGDS (0.72) | HPGDSPSMD14STAMBPCOPS5KMT2A | |
| SCHEMBL4145910 | 0.86 | HPGDS (0.67) | HPGDSPSMD14STAMBPCOPS5PARP1 | |
| Hydrochloric Acid SCHEMBL6086439 | 0.85 | HPGDS (0.71) | HPGDSPSMD14STAMBPCOPS5KMT2A | |
| SCHEMBL2200731 | 0.85 | HPGDS (0.75) | HPGDSPSMD14STAMBPCOPS5KMT2A | |
| SCHEMBL4410083 | 0.83 | HPGDS (0.67) | HPGDSPSMD14STAMBPCOPS5KMT2A | |
| SCHEMBL4721861 | 0.81 | HPGDS (0.64) | HPGDSPSMD14KMT2AMEN1 | |
| SCHEMBL30537997 | 0.80 | PSMD14 (0.66) | HPGDSPSMD14STAMBPCOPS5PARP1 | |
| SCHEMBL17629674 | 0.80 | PSMD14 (0.66) | HPGDSPSMD14STAMBPCOPS5PARP1 | |
| SCHEMBL30211275 | 0.79 | MAPT (0.53) | HPGDSPARP1KMT2AALDH1A1KDM4E | |
| SCHEMBL18987846 | 0.79 | HPGDS (0.62) | HPGDSPSMD14STAMBPCOPS5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824689-A | 3,8-DIHYROXYQUINOLINE AND DERIVATIVES, ANTICANCER AGENT, PREPARATION FROM 8-ALKOXYQUINOLINE-3-CARBOXAMIDE, HOFFMAN REARRANGEMENT, DIAZOTIZATION | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1998-10-20 | — | — | US | claimed |
| US-5824689-A | 3,8-DIHYROXYQUINOLINE AND DERIVATIVES, ANTICANCER AGENT, PREPARATION FROM 8-ALKOXYQUINOLINE-3-CARBOXAMIDE, HOFFMAN REARRANGEMENT, DIAZOTIZATION | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1998-10-20 | — | — | US | disclosed |