Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | HTR3A | P46098 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | POLR1A | O95602 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003564 | 1.00 | STS (0.37) | STSHTR3AKCNH2TP53MAPT | |
| SCHEMBL1003297 | 0.90 | KMT2A (0.36) | STSHTR3AKCNH2MAPTUSP30 | |
| Lithium Ion SCHEMBL1003296 | 0.89 | GPR119 (0.37) | STSHTR3AKCNH2MAPTUSP30 | |
| SCHEMBL1006680 | 0.88 | SMARCA2 (0.42) | STSTP53MAPTTHRBGPR119 | |
| SCHEMBL1006679 | 0.88 | SMARCA2 (0.42) | STSTP53MAPTTHRBGPR119 | |
| SCHEMBL1004355 | 0.85 | HTR3A (0.48) | HTR3AKCNH2GPR119POLR1A | |
| SCHEMBL1005157 | 0.85 | HTR3A (0.48) | HTR3AKCNH2GPR119POLR1A | |
| SCHEMBL1005158 | 0.85 | HTR3A (0.48) | HTR3AKCNH2GPR119POLR1A | |
| SCHEMBL1004469 | 0.85 | HTR3A (0.48) | HTR3AKCNH2GPR119POLR1A | |
| SCHEMBL4409740 | 0.80 | USP30 (0.43) | MAPTUSP30GPR119POLR1AEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061460-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | Albany Molecular Research, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008019372-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-02-14 | — | — | WO | disclosed |