Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850898 | 0.92 | TDP1 (0.56) | TDP1SLC7A5TYRLMNATSHR | |
| SCHEMBL28013153 | 0.90 | TDP1 (0.55) | TDP1SLC7A5TYRLMNATSHR | |
| SCHEMBL11350226 | 0.86 | SERPINE1 (0.53) | SLC7A5TYRALDH1A1 | |
| SCHEMBL8332481 | 0.83 | SLC7A5 (0.57) | TDP1SLC7A5HDAC8TYRLMNA | |
| SCHEMBL1422055 | 0.82 | SLC7A5 (0.64) | SLC7A5HDAC8TYRLMNAALPI | |
| SCHEMBL27680265 | 0.82 | SLC7A5 (0.67) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL4453960 | 0.82 | SLC7A5 (0.67) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL11349279 | 0.81 | SLC7A5 (0.57) | SLC7A5HDAC8CYP19A1LMNATSHR | |
| SCHEMBL11349283 | 0.81 | SLC7A5 (0.57) | SLC7A5HDAC8CYP19A1LMNATSHR | |
| SCHEMBL19031771 | 0.81 | SLC7A5 (0.57) | TDP1SLC7A5HDAC8LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036918-A1 | PEPTIDE DERIVATIVE | Vexon, Inc. (JP) | 2009-03-18 | — | — | EP | claimed |
| US-20080009448-A1 | Peptide Derivative | VEXON, INC. (50%) (JP) | 2008-01-10 | — | — | US | claimed |
| EP-2036918-A1 | PEPTIDE DERIVATIVE | Vexon, Inc. (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20080009448-A1 | Peptide Derivative | VEXON, INC. (50%) (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009448-A1 | Peptide Derivative | ARGLU1, NGLY1, NPR3 | TDP1 2092/4885SLC7A5 221/4885HDAC8 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.