Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405624 | 0.79 | ALDH1A1 (0.41) | MAPTNPSR1LMNAALDH1A1KMT2A | |
| SCHEMBL4415079 | 0.76 | CYP1A2 (0.39) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL4405823 | 0.75 | MEN1 (0.31) | MAPTKMT2AMEN1 | |
| SCHEMBL4404541 | 0.72 | CNR1 (0.38) | CNR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4414682 | 0.72 | CYP1A2 (0.36) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL28061180 | 0.71 | ALDH1A1 (0.43) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL4410876 | 0.69 | MAPK1 (0.43) | MAPTCNR2LMNATRPV1ALDH1A1 | |
| SCHEMBL4413128 | 0.69 | — | — | |
| SCHEMBL4406626 | 0.68 | LMNA (0.50) | MAPTLMNAALDH1A1GRM2KMT2A | |
| SCHEMBL11767534 | 0.67 | CNR2 (0.41) | MAPTCNR2LMNATRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |