Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25009055 | 0.85 | CYP1A2 (0.37) | CYP1A2POLBCYP2C19TDP1ALDH1A1 | |
| SCHEMBL4404213 | 0.83 | CYP1A2 (0.36) | CYP1A2POLBCYP2C19TDP1ALDH1A1 | |
| SCHEMBL4410852 | 0.80 | CYP1A2 (0.39) | CYP1A2POLBCYP2C19TDP1ALDH1A1 | |
| SCHEMBL4404572 | 0.78 | CYP1A2 (0.42) | CYP1A2POLBCYP2C19TDP1ALDH1A1 | |
| SCHEMBL14417046 | 0.77 | POLB (0.37) | CYP1A2POLBCYP2C19TDP1ALDH1A1 | |
| SCHEMBL4416627 | 0.75 | CYP1A2 (0.40) | CYP1A2POLBCYP2C19TDP1ALDH1A1 | |
| SCHEMBL12988914 | 0.72 | KMT2A (0.33) | CYP1A2ALDH1A1 | |
| SCHEMBL4400334 | 0.70 | — | — | |
| SCHEMBL4413261 | 0.69 | CNR2 (0.39) | ALDH1A1 | |
| SCHEMBL4406913 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133426-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | disclosed |
| US-11820773-B2 | Tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2023012081-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-09 | — | — | WO | disclosed |
| US-20220169650-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-06-02 | — | — | US | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169650-A1 | TRICYCLIC COMPOUNDS | SLC10A1, PKD1, CEL | CYP1A2 86/4885POLB 3198/4885CYP2C19 11/4885 |
| US-11820773-B2 | Tricyclic compounds | SLC10A1, PKD1, CEL | CYP1A2 86/4885POLB 3198/4885CYP2C19 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.